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KMID : 0653819910170010010
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Microorganisms and Industry
1991 Volume.17 No. 1 p.10 ~ p.18
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A comparative study of the major component of the protein secretion machinery, secY, in gram positive bacillus subtilis and gram negative escherichia coli.
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Suh Joo-Won
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Abstract
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A phylogenetic comparison of homologous protein can often supplement genetic and biochemical analysis by revealing conserved structures that are critical for function(Waugh et al., 1989). I therefore isolated a secY homologue from B. subtilis, a gram positive bacterium evolutionary distant from E. coli. The comparison and interplay between these two bacterial systems should contribute greatly to our understanding of the functions and interactions within systems evolved for protein translocation in both prokaryotic and eukaryotic organisms.
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